Inventors: Nicolae Manolescu, Serban Constantin Valeca, Rodica Anghel, Ion Balanescu ,Rodin Traicu, Dumitru Marculescu, Ioan Stefanescu
Class name: Drug, bio-affecting and body treating compositions inorganic active ingredient containing ; Publication date: 2008-09-04;Patent application number: 20080213390

Abstract:

A method is provided for utilizing Deuterium Depleted Water (DDW) as an adjuvant in cancer therapy and for reducing cytostatic toxicity. The method includes administration of DDW having a concentration of about 60 ppm, as a daily diet, to animals. The cancer therapy can include a mono-chemotherapy where a single drug or cytostatic is used or a poly-chemotherapy where more than one drug or cytostatic is used. The drug or cytostatic that are used for chemotherapy can include one or more of Cyclophosphamide, 5-Flourouracil, Farmarubicine and Vinblastine. The method can be used to treat different types of cancer.

Claims:
1-2. (canceled)
3. A method of utilizing deuterium depleted water for the manufacture of a medicament for reducing the toxicity of cytostatics by administering of water having 60 ppm concentration, before, during and after mono-chemotherapy with at least one of cyclophosphamide, 5-fluorauracil, farmarubicine and vinblastine, as a daily diet.

4. A method of utilizing of deuterium depleted water for the manufacture of a medicament for reducing the toxicity of cytostatics by administering of water having 60 ppm concentration, before, during and after poly-chemotherapy with at least one of cyclophosphamide, 5-fluorauracil, vincristine and vinblastine, as a daily diet.

5. A method of treating an organism having cancer comprising administering deuterium depleted water, before, during and after chemotherapy, as a daily diet.

Results
All of these studies and examinations show post-therapeutically improvement of the immune system of these animals receiving 60 DDW and cytostatics, and therefore, their therapeutical remission is extended. All of these beneficial effects provide a better protection against cytostatic toxicity. Thus, a better therapeutic index was obtained, which results in prolongation of pets’ lives and a remarkable improvement in the comfort of these animals that have different types of cancers.

The results obtained from the studies of the dogs confirm the results obtained from the studies of the rats, and show that 60 ppm DDW has certain properties for cancer organism detoxification, or for an organism that is subjected to the toxic stress generated by cytostatics (i.e., negative side effects) which are used in anti-cancer polychemotherapy.

Thus, 60 DDW can be used as an effective adjuvant, in reducing the toxicity of cytostatics that are used in cancer polychemotherapy, for all organisms including humans and pets.