Authors: Petcu Mihaela Doina *, Lucia Olariu*, Stela Cună***, P. Berdea ***, F. Muselin *, Iuliana Cretescu**, Mihaela Pup*, Ileana Brudiu*, Letitia Stana*
*Faculty of Veterinary Medicine, Timisoara
**Faculty of Animal Sciences and Biotechnologies, Timisoara
National Institute for Research and Development of Isotopic and MolecularTechnologies, Cluj
Bulletin UASVM, Veterinary Medicine 65(1)/2008

Abstract

The effects of cadmium pollution are highlighted in many studies, [7,14]. Cadmium, absorbed within the organism, inhibits the action of some antioxidant enzymes, especially those which contain SH and affect especially the liver and kidneys. The level of deuterium in tap water is 150 ppm and in deuterium depleted water are under 80 ppm.

Deuterium depleted water with a deuterium level of 30 ppm has an antioxidant effect on the organism [9, 10]. The present study has asses the effects of deuterium depleted water (30 ppm) on the deuterium blood level in the rats exposed to cadmium (20 ppm Cd/kg administered as CdCl2 solution in a single dose). The intoxication with cadmium modified the blood level of deuterium in the animals and the kidney, liver and spleen weight.

The blood level of deuterium was determined through weight spectroscopy with the spectrophotometer SMAD1. We observed a protective effect of deuterium depleted water on the rat organism, for preventive administration, as well as treatment and the important role in eliminating cadmium